鬼筆環(huán)肽-賴氨酸標(biāo)記

	貨號(hào)	5304	存儲(chǔ)條件	在零下15度以下保存, 避免光照
	規(guī)格	100 ug	價(jià)格	1164
	Ex (nm)		Em (nm)
	分子量	885.91	溶劑	DMSO
	產(chǎn)品詳細(xì)介紹

簡(jiǎn)要概述

產(chǎn)品基本信息

貨號(hào)：5304

產(chǎn)品名稱：鬼筆環(huán)肽-賴氨酸標(biāo)記

規(guī)格：100ug

儲(chǔ)存條件：-15℃避光防潮

保質(zhì)期：24個(gè)月

產(chǎn)品物理化學(xué)光譜特性

分子量：885.91

溶劑：DMSO

產(chǎn)品介紹

鬼筆環(huán)肽賴氨酸是一種方便的化合物，可用于開發(fā)各種鬼筆環(huán)肽衍生物，這些衍生物可用于研究細(xì)胞結(jié)構(gòu)和其他生物學(xué)應(yīng)用。它易于與胺反應(yīng)性染料，生物素和其他標(biāo)簽分子（例如NHS酯，異硫氰酸酯和磺酰氯等）反應(yīng)。鬼筆環(huán)肽是一種雙環(huán)七肽毒素，特異性結(jié)合在F-肌動(dòng)蛋白亞基之間的界面上，將相鄰的亞基鎖定在一起。鬼筆環(huán)肽與肌動(dòng)蛋白絲的結(jié)合比與肌動(dòng)蛋白單體的結(jié)合要緊密得多，從而導(dǎo)致肌動(dòng)蛋白亞基從絲端解離的速率常數(shù)降低，從而通過(guò)防止絲解聚而基本穩(wěn)定了肌動(dòng)蛋白絲。鬼筆環(huán)肽的性質(zhì)是研究F-肌動(dòng)蛋白在細(xì)胞中分布的有用工具，方法是用熒光類似物標(biāo)記鬼筆環(huán)肽并將其用于染色肌動(dòng)蛋白絲以進(jìn)行光學(xué)顯微鏡檢查。已經(jīng)證明，鬼筆環(huán)肽的熒光衍生物在定位活細(xì)胞或固定細(xì)胞中的肌動(dòng)蛋白絲以及在體外可視化單個(gè)肌動(dòng)蛋白絲方面非常有用。熒光鬼筆環(huán)肽衍生物已被用作高分辨率研究肌動(dòng)蛋白網(wǎng)絡(luò)的重要工具。 AAT Bioquest為多色成像應(yīng)用提供了多種具有不同顏色的熒光鬼筆環(huán)肽衍生物。

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